1. Population worldwide is rapidly aging, leading to an explosion of age-related diseases that not only reduce quality of life but may lead to disability or even death. This represents a serious threat for humanity and places an enormous strain on healthcare systems worldwide; consequently it is necessary to develop effective preventive or curative solutions as well as understand their underlying mechanisms.
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3. At present, cardiovascular disease is the most frequently seen age-related health condition, followed by neurodegenerative disorders and metabolic conditions like type 2 diabetes. Although progression of these diseases may seem inevitable, oftentimes its progression can be delayed or reversed through interventions like caloric restriction, exercise and pharmaceutical agents such as metformin or rapamycin.
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5. Age-related diseases share multiple common molecular features, such as mitochondrial dysfunction, defective autophagy, loss of proteostasis balance and altered intercellular communication. Targeting these features could provide an effective means of preventing and even reversing many age-related diseases.
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8. But for many elderly individuals, chronic conditions such as osteoarthritis, osteoporosis and diabetes can create significant morbidity and impairment of function, while in many instances being linked with decreased immune functioning.
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10. As a result, health care costs associated with these patients have seen dramatic increases, placing undue strain on both healthcare systems and society as a whole. Novel approaches that aim to slow the progression of diseases while alleviating associated burdens could represent a breakthrough for improving elderly quality of life while simultaneously cutting healthcare expenditures and stimulating economic growth.
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12. Old Age Diseases PDF;
13. People over 85 years of age are at high risk for chronic illnesses. Healthcare providers frequently encounter complex discussions when working with these patients regarding starting or stopping medications, ordering screening tests and referrals, informing families about placement options or discussing end of life care. Such discussions require having an intimate knowledge of both patient expectations and goals, life expectancy estimates as well as managing multiple chronic conditions with limited resources. Elderly alarm
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15. Website: https://familyr.co.nz/